OPTIMIZATION OF GELATIN AND CROSSLINKER CONCENTRATIONS IN A GELATIN/ALGINATE-BASED BIOINK WITH POTENTIAL APPLICATIONS IN A SIMPLIFIED SKIN MODEL

Optimization of Gelatin and Crosslinker Concentrations in a Gelatin/Alginate-Based Bioink with Potential Applications in a Simplified Skin Model

Three-dimensional bioprinting allows for the fabrication of structures mimicking tissue architecture.This study aimed to develop a gelatin-based bioink for a bioprinted simplified skin model.The bioink printability and chemical-physical properties were evaluated by varying the concentrations of gelatin (10, 15, and 20%) in a semi-crosslinked algina

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Outcomes of hyperbolic tapering of antidepressants

Background: In patients attempting to discontinue their antidepressant medication, there have been no prospective studies on patterns of withdrawal as a function of the rate of antidepressant reduction during the tapering trajectory, and moderators thereof.Objective: To investigate withdrawal as a function of gradual dose reduction.Design: Prospect

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